Methadone Drug Addiction .com

Has any one ever experienced withdrawal from a methadone maintainence program? If you have can you tell me if it was really as bad as I have heard?

When you're on a methadone maintenance program, you are slowly weaned off of it as the methadone dose is slowly decreased so that you don't experience the withdrawals that you would had you simply stopped whatever narcotic it was that you were on. That's the whole purpose of methadone as a way to get off of narcotics.

2008-01-14 09:39:05 by Toronto Joe

Addiction to methadone can be viewed as a disease that attacks the central nervous system, and common symptoms include gastrointestinal distress ...

i was taking 60mg of methadone for 4 years ( not legally) then my supply stopped. ive been trying to detox by taking oxycontin in moderation. starting with 80mg, then to 40, 30, 20, 10, 5, and yesterday was my last day. Will i still feel withdrawal symptoms, such as vomiting, weakness, and insomnia?

You better believe you are. You are not going to feel the extent of the Methadone withdraw until 3 days of none and since you are super dependant on the methadone
(You are super dependant on any opiate now < you have a billions of receptors and you will withdraw off a darvocet)

You are going to withdraw off the Oxycodone and it is going to be horrible! The large gaps in your receptors cannot be filled by the faster acting /less efficient weaker oxycodone and you are going to withdraw worse! The Methadone would have ran it's course and kept these things filled to the end, not now. You have two drugs now competeting for the same receptor sites making withdrawal worse as the drugs are being depleted. Two weeks at least, and the Oxycodone is going to make it worse now. ANd the first few days of this you are getting the illusion it is working for the drugs are in competition (Making you feel great) and working until the levels drop. And than God help you.

What you did was take a higher hitting opiate and throw your pain receptors completely out of wack, for they are use to; and you are use to the flat methadone, and you might as well been giving your body nitrous oxide injections and than slammed on your brakes; now you are going to get full blown oxycodone withdrawal and it is going to be hell, and than your going to get the methadone. You still have 10mg's of Methadone in you and that is going to be hell to get off of.

Why in the world would you take Oxycodone????????? These are to completely different acting drugs. In about 12 hours or less you are going to get the most excruciating stomach pains you ever felt in your entire life. Taking the Oxycodone completely threw the relatively light 60mg's Methadone withdrawal right off the rails. You can do this but not like this! You would have to take the Oxy mg's versus the Methadone MG's and flatten the mg's of the Oxycodone like a pancake.

TRUST ME!

2009-03-20 17:36:32 by jeff

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My girlfriend has been on methadone for about 2-3 months for chronic pain. At max, she was taking 60-80mgs a day. Everything I read on the internet regarding withdrawal symptoms is regarding people who have been on 200mgs a day for years. She is obviously in a different criteria. Does anyone have a good resource regarding what to expect, and the best ways to get off of short-term methadone use in relation to withdrawal symptoms it will product?

DO NOT GOTO A METHADONE CLINIC...only about 10% have a legit program that works.Most clinic are just about the money.I will give you 2 options or advice.If she was taking the methadone for pain and it was prescribed,then the doctor should wean her down...if he/she wont,then another doctor will since it was prescribed.However,if you were getting them off the street,a doctor will refer you to a clinic.I have posted a link to a drug forum and a detox forum with people who have experience.My suggestion to you is KRATOM.Kratom is a great herb that has saved my life.Be aware that kratom can be addicting to,so please do your research before attempting kratom use.I will also post a link to kratom info.Its long,but you can scroll right down to its uses and pharmacology section.Its being considered as a methadone replacement.Methadone is BAD,BAD and by the way 60 to 80mgs of methadone a day aint a cake walk to come off from.It may seem small compared to the other doses...but it definately aint fun coming off 40mgs a day.That was extremely hard for me.Enough to NEVER do methadone again.OH and I was only on it for about 28days...but in fairness I was using methadone to come off hydrocodone SO i already had a dependant to hydrocodone...but coming off hydrocodone was a cake walk in the past compared to methadone.But me being stupid,listened to an aquaintance the recommended methadone to fight my withdrawal symptom...I thought.WHY NOT?Bad choice on my part.I pray that she comes off ok one way or another.All I can say is kratom worked for me.Good luck

Oh and BALI strain of kratom is best for opiate withdrawals

2007-12-24 17:43:52 by Mike N

I have detoxed from methadone but want to know how long the withdrawal sympts will last? No chance of relapsing!

I know people who went from 120 to 40 then down and without at least 10mg's a day after 1 year still have withdrawals % people I know who went off went back to 10 or 20 mg's. I was once on 440 mg's and got off by switching to 300mcg's of Duragesic as whether i took 220 or 440 I got same relief as it has ceiling. I took for pain, not addiction. Tell dr. to let you try at least 25mcg duragesic then withdrawal from there..I never told my Dr. i was with drawing myself off methadone just cutting in half and was off totally in a month without any effects. defiantly worse drug to come off of. 4 days after cold turkey you will wish you were dead. My friend went to e.r and they gave him 2 diliaudid shots and with Dr. approval as hospitals will not give c2 narcs except percs he got 100 mcg patch to use for 1 month and then went to 75-50-25-percocet til off.

2009-03-19 07:29:40 by buck492

I have a theory and was wondering if it would work. Methadone withdrawal is mainly caused from the body producing too much norepinephrine because opiate cause your body to not make as much and it has to kick up the production when you get addicted to opiates, which is why withdrawals happens. If someone were to take pseudoephedrine for a long while before stopping methadone cold turkey and then stop taking the pseudoephedrine too, would this help the body to not produce so much norepinephrine? Since sudafed (norepinephrine) causes an increase in norepinephrine, it would seem that one would go through a withdrawal from it constiting of too little norepinephrine and maybe the two would counteract each other, or at least make the methadone withdrawals a little easier as they are impossible for me at this time. What do you guys and girls think?
Hey Tim L....

I know for a fact that pseudoephedrine works by stimulating release of norepinephrine from the neuro-endocrine system. Also, a significant part of methadone withdrawal is cause from the body producing too much norepinephrine, which is why clonidine is sometimes prescribed to help withdrawals. Read up on your medical info or ask a doctor before assuming you are right. I've done a lot of research, believe me!

Psuedoephedrine is NOT norepinephrine nor does it cause an increase in norepineprine. Methadone withdrawal is NOT caused by excessive production of norepinephrine. Every part of this theory is wrong.

UPDATE:

It's not clear why you would ask a question if you only intend to reject the answer, so I'll make these my last comments:

Saying you "know for a fact" does not make you claims true, nor more credible. If any of this theory were supported by evidence you could have easily cited references, but you have not.

Methadone is actually a norepinephrine reuptake inhibitor, which means it *increases* the activity of norpinephrine systems. Sympathetic amine activity of some opioids is a common topic in pain research.

Removing methadone after chronic administration ends the norepinephrine reuptake blockade, which, if anything, risks *decreasing* adrenal system activity. Generalized adrenal stimulation from opiate withdrawal may counteract this, but the main point is that norepinephrine is not particularly relevant to methadone withdrawal, nor is it generally the cause of opiate withdrawal symptoms. It is at most one part of a cascade of neurochemical changes during withdrawal, and it’s quite possibly only secondary to the actual causes of symptoms.

It's harder to analyze your claims about sudafed because you've gone from claiming that it *is* norepinephrine to claiming that it only stimulates release of norepinephrine. Sudafed most certainly is not norepinephrine, and while it can precipitate the release of epinephrine and other sympathetic amines, its main action is to mimic the action of sympathetic amines (like norepinephrine). The following abstract cited below, just as an example, discusses both actions.

Although clonidine as some effects on epinephrine and norephinephrine levels, it is useful during withdrawal because it is an alpha-2 agonist which helps reduce sweating, shaking, high blood pressure, etc. Epinephrine and norepinephrine are part of the story of how alpha-2 agonists work, but “decreasing norepinephrine” is not what makes clonidine helpful for withdrawal.

2006-10-27 02:19:45 by Jordan M