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FDA issues advisory on methadone.(News)(Food and Drug Administration): An article from: Clinical Psychiatry News [H] [T] [M]

Jane Salodof MacNeil (Digital) Thomson Gale 2007-01-01
Release date: 2007-02-06


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Answers

HOw do you overcome the side effects of methadone usage?

Someone I love is using methadone to overcome oxycotin addiction. She's been on the program for 7 months and has not slipped. Her side effects are awful. Sweating, nausea, dizziness and fatigue. This seems like coming off of drugs instead of helping her to overcome the initial addiction. Anybody out there that can recommend anything? Thankx for your time and consideration Folks>I so appreciate it.


I went through the same thing after a bad accident. What worked for me was vitamins namely C,E,B complex and a liquid colloidal complex. The withdraw will slowly get better, what your loved one needs most is understanding and support from the ones she loves. exersize and a support group like N.A. is a big help also. Be good and God bless.

Methadone Effects : Methadone Effects on the Cardiovascular System


The effects of methadone on the cardiovascular system are similar to the effects of alcohol or other central nervous system depressants, and it ...

What are the side effects of methadone?

I know methadone is used by a lot of people who are getting themselves treated for their opioid dependence. It can also be used for the treatment of pain. I just want to know what the side effects of methadone are and is this safe to use? Wouldn't the user get addicted to methadone also?


There are indeed some side effects that methadone is associated with. These are: nausea, pruritus, constipation, sedation, confusion, and respiratory depression. Flushing and excess sweating may also occur in patients who use methadone orally. If the prescription is followed properly by the patient, he wouldn't get addicted to it. Methadone is safe only when it is not abused by the patient.

What are common negative effects of Methadone for pain after a while?

I have been taking methadone for IP (Intractible Pain) for a while and wanted to know if the negative side effects I am experiencing, along with the fact that it is not working properly is normal- PLEASE LET ME KNOW


here is what I found:
Side effects associated with methadone are similar to those incurred with other mu-opioid agonists, including pruritus, nausea, constipation, confusion, sedation, and respiratory depression. Excess sweating (diaphoresis) and flushing are common with oral methadone dosing. Caution should be taken with initiation of therapy and dosage increases because severe toxicities may not become apparent for two to five days. In a study of patients converted to methadone therapy in an outpatient setting, 20 of 29 participants experienced some degree of toxicity, most frequently mild drowsiness, during initial titration.29 Side effects such as sedation and respiratory depression are increased when methadone is combined with alcohol or other drugs. An Australian study30 found benzodiazepines present in 74 percent of deaths related to methadone and urged particular caution when methadone was prescribed with benzodiazepines.

As far as effectiveness, Unlike morphine, it usually is not necessary to adjust the dosage of methadone in patients with renal insufficiency. The duration of analgesia is approximately three to six hours when methadone therapy is initiated, and this duration typically extends to eight to 12 hours with repeated dosing. In a study of cancer patients, an average of 2.4 doses per day was required to maintain adequate pain control.

Hope this helps. http://www.aafp.org/afp/20050401/1353.ht ml

i need to know about the side effects im experiencing with methadone?

im having serious side effects with methadone and the docs dont believe it because these side effects are not heard of.


Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.
Call your doctor at once if you have any of these serious side effects:

shallow breathing;
hallucinations or confusion; or
fast or pounding heartbeats, chest pain, trouble breathing, feeling light-headed, fainting.
Other, less serious side effects may be more likely to occur, such as:

feeling anxious, nervous, or restless;
sleep problems (insomnia);
dizziness, drowsiness, or weakness;
dry mouth, nausea, vomiting, diarrhea, constipation, loss of appetite; or
decreased sex drive, impotence, or difficulty having an orgasm.
This list is not complete and other side effects may occur. Tell your doctor about any unusual or bothersome side effect.

What are the various side effects of methadone?

I know that this is used for the treatment of drug addiction or as a painkiller. However, I have also heard that there are a lot of side effects.


Methadone, when used properly, won't produce life-threatening side effects. However it does have some and these are as follows:

* pruritus
* constipation
* nausea
* confusion
* respiratory depression
* sedation
* mood changes
* dry mouth
* difficulty urinating
* vision problems
* flushing
* stomach pain
* weight gain

When using this medication, caution must always be exercised especially with regard to increase of dosage.


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  • Side Effects of Methadone and Suboxone: Constipation ...

    When I ask my patients about side effects of methadone and buprenorphine (active ingredient in Suboxone and Subutex), the most common one they report is constipation. Nearly all people on any opioids have constipation. This is because the bowels contain opioid receptors, and when they are stimulated with opioids, the bowels relax and don’t contract as much.

    So what can be done?

    Of course, drinking more fluids will help. Then, try adding more fiber to your diet. Either eat more fresh fruits and vegetables, or get some of the fiber-containing agents. Some brand names include FiberCon, Metamucil, and Citrucel.

    If that doesn’t get things moving, try adding a stool softener. If no results after all of these, consider trying the Miralax powder. Some people need to take it on a regular basis to keep their bowels moving. Some patients use a teaspoon of mineral oil every morning to keep them moving.

    It’s a good idea to see a primary care or gastrointestinal doctor at least once, to rule out causes other than medication. If you have blood in your stool, weight loss, or a family history of colon cancer, we don’t want to ignore the possibility that something more serious could be causing bowel problems.

    ...

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